BDBM4811 (Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrol-3-yl]-propionic acid::3-(2,4-dimethyl-5-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid::CHEMBL274654::SU6668

SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccccc23)c(C)c1CCC(O)=O

InChI Key InChIKey=NHFDRBXTEDBWCZ-ZROIWOOFSA-N

Data  22 IC50

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4811   

TargetAurora kinase C(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL

LigandBDBM4811((Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-y...)Copy SMILESCopy InChI

Affinity DataIC50:  210nMAssay Description:Inhibition of Aurora C in the presence of 5uM ATPMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
PC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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